代表性成果

合作成果连年增长，不完全统计已服务客户发表文章300多篇

趋势

转录组是最常用的研究工具，表观基因组量少质高，表观转录后起直追

 

产品

质量

总影响因子>3500, 平均IF=8.09

 

  • 发表

    时间

    影响

    因子

    		 杂志期刊 单位 文章标题
    2024 11.70 Science Advances 宁波大学海洋学院 A global transcriptional activator involved in the iron homeostasis in cyanobacteria
    2024 5.70 Clinical Epigenetics 重庆医科大学 The chromatin accessibility and transcriptomic landscape of the aging mice cochlea and the identication of potential functional super-enhancers in age-related hearing loss
    2024 9.50 Experimental & Molecular Medicine 哈尔滨医科大学 YAP1 inhibits the senescence of alveolar epithelial cells by targeting Prdx3 to alleviate pulmonary fibrosis
    2024 10.70 Redox Biology 中国药科大学 Lactate drives epithelial-mesenchymal transition in diabetic kidney disease via the H3K14la/KLF5 pathway
    2024 4.10 Pest Management Science 河南农业大学 Alternative splicing of the conserved drug-resistant orthologue FpNcb2 is associated with its nuclear accumulation of products and full virulence of Fusarium pseudograminearum
    2024 12.30 Genome Medicine Jianbo Tian:武汉大学人民医院
    Kun Chen：浙江大学医学院附属第二医院    		 Developing an optimal stratification model for colorectal cancer screening and reducing racial disparities in multi-center population-based studies
    2024 24.30 Drug Resistance Updates 中国医学科学院北京协和医学院 KLF12 Interacts with TRIM27 to affect Cisplatin Resistance and Cancer Metastasis in Esophageal Squamous Cell Carcinoma by regulating L1CAM Expression
    2024 9.10 Science China-Life Sciences 华中科技大学同济医学院附属同济医院 Fibroblast-localized lncRNA CFIRL promotes cardiac fibrosis and dysfunction in dilated cardiomyopathy
    2024 5.00 Translational Oncology 大连医科大学第二医院 STIL facilitates the development and malignant progression of triple-negative breast cancer through activation of Fanconi anemia pathway via interacting with KLF16
    2024 5.60 Journal of Cellular Physiology  四川省人民医院 KLF13 promotes VSMCs phenotypic dedifferentiation by directly binding to the SM22α promoter

  • 发表

    时间

    影响

    因子

    		 杂志期刊 单位 文章标题
    2024 4.4 Frontiers in Pharmacology 福建医科大学 Involvement of autophagy in mesaconitine-induced neurotoxicity in HT22 cells revealed through integrated transcriptomic, proteomic, and m6A epitranscriptomic profiling
    2024 4.6 Toxics 福建医科大学 Integrating Epigenetics, Proteomics, and Metabolomics to Reveal the Involvement of Wnt/β-Catenin Signaling Pathway in Oridonin-Induced Reproductive Toxicity
    2024 preprint bioRxiv  中国医科大学附属第一医院 FKBP11 targeted plasma cells promotes abdominal aortic aneurysmprogression through an m6A-dependent mechanism
    2024 5.7 Molecular Medicine 武汉大学人民医院 Comprehensive analysis of m6A modification in lipopolysaccharide-induced acute lung injury in mice
    2024 7 Cell Death Discovery 苏州大学附属儿童医院 METTL14 promotes neuroblastoma formation by inhibiting YWHAH via an m6A-YTHDF1-dependent mechanism
    2024 3.5 Genes 福建医科大学附属南平市第一医院 Unveiling the Impact of ApoF Deficiency on Liver and Lipid Metabolism: Insights from Transcriptome-Wide m6A Methylome Analysis in Mice
    2024 3.4 Experimental Eye Research 河南省人民医院 TGF-β2-induced alteration of m6A methylation in hTERT RPE-1 cells
    2024 7.3 Plant Cell and Environment 北京林业大学 N6-methyladenosine mRNA methylation positively regulated the response of poplar to salt stress
    2023 4.6 Journal of Dermatological Science 华中科技大学同济医学院附属同济医院 WTAP-mediated m6A modification of IFNE is required for antiviral defense in condyloma acuminata

     

     

  • 年份 影响因子 杂志期刊 单位 文章标题
    2023 17.10 ACS Nano 协和医院 Dual-Targeted Nanodiscs Revealing the Cross-Talk between Osteogenic Differentiation of Mesenchymal Stem Cells and Macrophages
    2023 15.10 advanced science 重庆医大口腔医院 Hypoxia Drives Material-Induced Heterotopic Bone Formation by Enhancing Osteoclastogenesis via M2/Lipid-Loaded Macrophage Axis
    2023 15.10 Advanced science 上海药物研究所 Elevated Nuclear PHGDH Synergistically Functions with cMyc to Reshape the Immune Microenvironment of Liver Cancer
    2023 15.10 Advanced science 协和医院 Ferroptosis-Enhanced Immunotherapy with an Injectable Dextran-Chitosan Hydrogel for the Treatment of Malignant Ascites in Hepatocellular Carcinoma
    2023 15.10 Advanced science 中山大学第七医院 PUM1 Promotes Tumor Progression by Activating DEPTOR-Meditated Glycolysis in Gastric Cancer
    2023 15.10 Advanced science 安徽医科大学 FGF9 Recruits β-Catenin to Increase Hepatic ECM Synthesis and Promote NASH-Driven HCC
    2023 10.60 Clinical & Trans Med 协和医院 Therapeutic targeting of CNBP phase separation inhibits ribosome biogenesis and neuroblastoma progression via modulating SWI/SNF complex activity
    2023 13.20 Emerging Microbes & Infections 武汉大学 NSUN2-mediated m5C methylation of IRF3 mRNA negatively regulates type Iinterferon responses during various viral infections
    2023 15.50 Microbiome 西北农林科技大学 High-fat diet-disturbed gut microbiota-colonocyte interactions contribute to dysregulating peripheral tryptophan-kynurenine metabolism
    2023 16.60 Nature Communications 昆明植物所 A natural biological adhesive from snail mucus for wound repair
    2023 13.80 Plant Biotechnology Journal 武汉大学 Rice DSP controls stigma, panicle and tiller primordium initiation
    2023 10.50 Plant Communications 华中农业大学 Long-distance control of potato storage organ formation by SELF PRUNING 3D and FLOWERING LOCUS T-like 1
  • 年份 影响因子 杂志期刊 单位 标题
    2023 16.60 Nature Communications 中南大学湘雅医院 Senescent immune cells accumulation promotes brown adipose tissue dysfunction during aging
    2023 13.20 Emerging Microbes & Infections 武汉大学 NSUN2-mediated m5C methylation of IRF3 mRNA negatively regulates type Iinterferon responses during various viral infections
    2023 12.40 CELL DEATH AND DIFFERENTIATION 中国医科大学 BAP18 facilitates CTCF-mediated chromatin accessible to regulate enhancer activity in breast cancer
    2023 8.80 Cell Reports 陕西师范大学 A conserved brassinosteroid-mediated BES1-CERP-EXPA3 signaling cascade controls plant cell elongation
    2023 10.60 CLINICAL AND TRANSLATIONAL MEDICINE 华中科技大学同济医学院附属协和医院 Therapeutic targeting of CNBP phase separation inhibits ribosome biogenesis and neuroblastoma progression via modulating SWI/SNF complex activity
    2023 11.40 EMBO Journal 中南大学湘雅医院 Splicing factor YBX1 regulates bone marrow stromal cell fate during aging
    2023 5.60 International Immunopharmacology 重庆医科大学第一附属医院 GATA6 promotes fibrotic repair of tracheal injury through NLRP3 inflammasome-mediated epithelial pyroptosis
    2023 16.60 Nature Communications 武汉大学人民医院 IRX2 regulates angiotensin II-induced cardiac fibrosis by transcriptionally activating EGR1 in male mice
    2023 6.10 Neurobiology of Disease 重庆医科大学附属第一医院 MBD5 regulates NMDA receptor expression and seizures by inhibiting Stat1 transcription
    2023 9.40 New Phytologist 浙江大学 Rice chromatin protein OsHMGB1 is involved in phosphate homeostasis and plant growth by affecting chromatin accessibility
    2023 13.80 Plant Biotechnology Journal 武汉大学 Rice DSP controls stigma, panicle and tiller primordium initiation
    2023 10.90 Experimental Hematology & Oncology 中国医学科学院国家癌症中心 Elevated expression of the RNA-binding protein IGF2BP1 enhances the mRNA stability of INHBA to promote the invasion and migration of esophageal squamous cancer cells
  • 年份 影响因子 杂志期刊 单位 文章标题
    2024 24.8 Science Immunology 华中科技大学同济医学院协和医院 Targeted depletion of PD-1–expressing cells induces immune tolerance through peripheral clonal deletion
    2024 64.5 Cell 复旦大学附属中山医院

    Neutrophil profiling illuminates anti-tumor antigen-presenting potency