代表性成果

合作成果连年增长，不完全统计已服务客户发表文章300多篇

趋势

转录组是最常用的研究工具，表观基因组量少质高，表观转录后起直追

 

产品

质量

总影响因子>3500, 平均IF=8.09

 

  • 年份 影响因子 杂志期刊 单位 文章标题
    2024 4.20 BBA - Molecular Basis of Disease 空军军医大学（第四军医大学） Follicular CD8+ T cells promote immunoglobulin production and demyelination in multiple sclerosis and a murine model
    2024 9.30 Pharmacological Research  四川大学华西医院 Histone methyltransferase MLL4 protects against pressure overload-induced heart failure via a THBS4-mediated protection in ER stress
    2024 14.00 Biomaterials 四川大学 H2Se-evolving bio-heterojunctions promote cutaneous regeneration in infected wounds by inhibiting excessive cellular senescence
    2024 18.90 Bioactive Materials 四川大学华西医院 Mitochondria-engine with self-regulation to restore degenerated intervertebral disc cells via bioenergetic robust hydrogel design
    2024 18.90 Bioactive Materials 上海交通大学医学院附属第六人民医院 Targeting micromotion for mimicking natural bone healing by using NIPAM/Nb2C hydrogel
    2024 9.30 Journal of Neuroinflammation 中国医科大学附属盛京医院 Protecting effects of 4-octyl itaconate on neonatal hypoxic-ischemic encephalopathy via Nrf2 pathway in astrocytes
    2024 10.60 Clinical and Translational Medicine 南京医科大学附属第一医院 A 3′-pre-tRNA-derived small RNA tRF-1-Ser regulated by 25(OH)D promotes proliferation and stemness by inhibiting the function of MBNL1 in breast cancer
    2024 30.80 Nature Genetics 浙江省农业科学院 Differential selection of yield and quality traits has shaped genomic signatures of cowpea domestication and improvement
    2024 12.70 Bone Research 中南大学湘雅医院 Kdm6a-CNN1 axis orchestrates epigenetic control of trauma-induced spinal cord microvascular endothelial cell senescence to balance neuroinflammation for improved neurological repair
    2024 12.40 Theranostics 第三军医大学（陆军军医大学）西南医院 Neutrophil extracellular trap-mediated impairment of meningeal lymphatic drainage exacerbates secondary hydrocephalus after intraventricular hemorrhage
    2024 15.30 International Journal of Surgery 福建省立医院 Single Dual-specific Anti-PD-L1/TGF-β Antibody Synergizes with Chemotherapy as Neoadjuvant Treatment for Pancreatic Ductal Adenocarcinoma: a Preclinical Experimental Study
    2024 12.40 Molecular Therapy 华中科技大学附属同济医学院同济医院 Nuclear AGO2 promotes myocardial remodeling by activating ANKRD1 transcription in failing hearts

  • 发表

    时间

    影响

    因子

    		 杂志期刊 单位 文章标题
    2024 4.4 Frontiers in Pharmacology 福建医科大学 Involvement of autophagy in mesaconitine-induced neurotoxicity in HT22 cells revealed through integrated transcriptomic, proteomic, and m6A epitranscriptomic profiling
    2024 4.6 Toxics 福建医科大学 Integrating Epigenetics, Proteomics, and Metabolomics to Reveal the Involvement of Wnt/β-Catenin Signaling Pathway in Oridonin-Induced Reproductive Toxicity
    2024 preprint bioRxiv  中国医科大学附属第一医院 FKBP11 targeted plasma cells promotes abdominal aortic aneurysmprogression through an m6A-dependent mechanism
    2024 5.7 Molecular Medicine 武汉大学人民医院 Comprehensive analysis of m6A modification in lipopolysaccharide-induced acute lung injury in mice
    2024 7 Cell Death Discovery 苏州大学附属儿童医院 METTL14 promotes neuroblastoma formation by inhibiting YWHAH via an m6A-YTHDF1-dependent mechanism
    2024 3.5 Genes 福建医科大学附属南平市第一医院 Unveiling the Impact of ApoF Deficiency on Liver and Lipid Metabolism: Insights from Transcriptome-Wide m6A Methylome Analysis in Mice
    2024 3.4 Experimental Eye Research 河南省人民医院 TGF-β2-induced alteration of m6A methylation in hTERT RPE-1 cells
    2024 7.3 Plant Cell and Environment 北京林业大学 N6-methyladenosine mRNA methylation positively regulated the response of poplar to salt stress
    2023 4.6 Journal of Dermatological Science 华中科技大学同济医学院附属同济医院 WTAP-mediated m6A modification of IFNE is required for antiviral defense in condyloma acuminata

     

     

  • 发表

    时间

    影响

    因子

    		 杂志期刊 单位 文章标题
    2024 11.70 Science Advances 宁波大学海洋学院 A global transcriptional activator involved in the iron homeostasis in cyanobacteria
    2024 5.70 Clinical Epigenetics 重庆医科大学 The chromatin accessibility and transcriptomic landscape of the aging mice cochlea and the identication of potential functional super-enhancers in age-related hearing loss
    2024 9.50 Experimental & Molecular Medicine 哈尔滨医科大学 YAP1 inhibits the senescence of alveolar epithelial cells by targeting Prdx3 to alleviate pulmonary fibrosis
    2024 10.70 Redox Biology 中国药科大学 Lactate drives epithelial-mesenchymal transition in diabetic kidney disease via the H3K14la/KLF5 pathway
    2024 4.10 Pest Management Science 河南农业大学 Alternative splicing of the conserved drug-resistant orthologue FpNcb2 is associated with its nuclear accumulation of products and full virulence of Fusarium pseudograminearum
    2024 12.30 Genome Medicine Jianbo Tian:武汉大学人民医院
    Kun Chen：浙江大学医学院附属第二医院    		 Developing an optimal stratification model for colorectal cancer screening and reducing racial disparities in multi-center population-based studies
    2024 24.30 Drug Resistance Updates 中国医学科学院北京协和医学院 KLF12 Interacts with TRIM27 to affect Cisplatin Resistance and Cancer Metastasis in Esophageal Squamous Cell Carcinoma by regulating L1CAM Expression
    2024 9.10 Science China-Life Sciences 华中科技大学同济医学院附属同济医院 Fibroblast-localized lncRNA CFIRL promotes cardiac fibrosis and dysfunction in dilated cardiomyopathy
    2024 5.00 Translational Oncology 大连医科大学第二医院 STIL facilitates the development and malignant progression of triple-negative breast cancer through activation of Fanconi anemia pathway via interacting with KLF16
    2024 5.60 Journal of Cellular Physiology  四川省人民医院 KLF13 promotes VSMCs phenotypic dedifferentiation by directly binding to the SM22α promoter
  • 年份 影响因子 杂志期刊 单位 标题
    2024 4.10 Pest Management Science 河南农业大学 Alternative splicing of the conserved drug-resistant orthologue FpNcb2 is associated with its nuclear accumulation of products and full virulence of Fusarium pseudograminearum
    2024 16.60 Nature Communications 中山大学附属第三医院 FTO deficiency in older livers exacerbates ferroptosis during ischaemia/reperfusion injury by upregulating ACSL4 and TFRC
    2024 24.30 Drug Resistance Updates 中国医学科学院北京协和医学院 KLF12 Interacts with TRIM27 to affect Cisplatin Resistance and Cancer Metastasis in Esophageal Squamous Cell Carcinoma by regulating L1CAM Expression
    2024 5.00 Translational Oncology 大连医科大学第二医院 STIL facilitates the development and malignant progression of triple-negative breast cancer through activation of Fanconi anemia pathway via interacting with KLF16
    2024 5.60 Journal of Cellular Physiology  四川省人民医院 KLF13 promotes VSMCs phenotypic dedifferentiation by directly binding to the SM22α promoter
    2024 7.40 Plant Physiology 东北林业大学 Acetylation of transcription factor BpTCP20 by acetyltransferase BpPDCE23 modulates salt tolerance in birch
    2024 6.70 PLoS Pathogens 南京医科大学 KSHV vIL-6 promotes SIRT3-induced deacetylation of SERBP1 to inhibit ferroptosis and enhance cellular transformation by inducing lipoyltransferase 2 mRNA degradation
    2024 9.70 Cancer Letters 武汉大学 Glutamine inhibition combined with CD47 blockade enhances radiotherapy-induced ferroptosis in head and neck squamous cell carcinoma
    2024 8.70 Horticulture Research 东北林业大学 Phosphorylation of birch BpNAC90 improves the activation of gene expression to confer drought tolerance
    2024 8.00 Cellular and Molecular Life Sciences 华中科技大学同济医学院生殖健康研究所 RNA m6A modification regulates L1 retrotransposons in human spermatogonial stem cell differentiation in vitro and in vivo
    2024 15.10 Advanced Science 重庆医科大学第一附属医院 SHMT2 Mediates Small-Molecule-Induced Alleviation of Alzheimer Pathology Via the 5′UTR-dependent ADAM10 Translation Initiation
    2023 10.90 Experimental Hematology & Oncology 中国医学科学院国家癌症中心 Elevated expression of the RNA-binding protein IGF2BP1 enhances the mRNA stability of INHBA to promote the invasion and migration of esophageal squamous cancer cells
  • 年份 影响因子 杂志期刊 单位 文章标题
    2024 24.8 Science Immunology 华中科技大学同济医学院协和医院 Targeted depletion of PD-1–expressing cells induces immune tolerance through peripheral clonal deletion
    2024 64.5 Cell 复旦大学附属中山医院

    Neutrophil profiling illuminates anti-tumor antigen-presenting potency